Title: On the regularity of weak solutions of the 3D Navier-Stokes equations in the largest critical space. Abstract: Since the pioneering work of Leray, the problem of regularity of weak solutions to the 3D Navier-Stokes equations has been a subject of serious investigation. We will review some classical regularity results and prove extensions of the Leray-Ladyzhenskaya-Prodi-Serrin criteria in Besov spaces.