Fragmentation of Bacterial Emboli and Biofilms in Flow

Abstract:
Klebsiella pneumoniae is one of the most common causes of
intravascular catheter infections, potentially leading to
life-threatening bacteremia. These bloodstream infections dramatically
increase the mortality of illnesses and often serve as an engine for
sepsis. Our current research considers models for both suspended
emboli and sessile biofilms.

In this talk I will focus on the progress of our investigation into
properties of the the model equations for suspended bacterial
emboli. In particular, I will focus on a) our evidence that a widely
used post-fragmentation distribution is incorrect, b) accurate
characterization of the fractal properties for the aggregates, and
(time permitting) c) self-similar solutions to the equations. Lastly,
I will briefly discuss the connections with our other project on
biofilm separation.